Skip to Content
Home > Health Resources > Antidiarrheals for Irritable Bowel Syndrome
View Additional Section Content
Antidiarrheal medicines, such as atropine and diphenoxylate
(such as Lomotil), eluxadoline (such as Viberzi), and loperamide (such as Imodium), slow intestinal movements.
This allows stool to stay in the intestine longer, allowing more water to be
absorbed, which makes the stool formed rather than watery when it is
passed. Antidiarrheals can help with diarrhea in IBS.footnote 1
Atropine and diphenoxylate may cause dry skin, itching, dizziness, drowsiness,
nausea, or vomiting. Psychological dependence may occur in high doses.
Loperamide may cause abdominal (belly) pain, dry mouth, nausea, vomiting, or
dizziness. These side effects are usually minor and do not last long. This
medicine may not help people who have alternating periods of diarrhea and
constipation, because it may make the constipation worse.
These medicines may be dangerous if they are used by people who
have certain types of intestinal infections or who have
inflammatory bowel disease. You should not use these
medicines if you have a fever or if you have blood in your stool.
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
American College of Gastroenterology (2009). An evidence-based systematic review on the management of irritable bowel syndrome. American Journal of Gastroenterology, 104(Suppl 1): S8-S35.
ByHealthwise StaffPrimary Medical ReviewerE. Gregory Thompson, MD - Internal MedicineAdam Husney, MD - Family Medicine
Current as ofMay 5, 2017
Current as of:
May 5, 2017
E. Gregory Thompson, MD - Internal Medicine & Adam Husney, MD - Family Medicine
To learn more about Healthwise, visit Healthwise.org.
© 1995-2017 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Our interactive Decision Points guide you through making key health decisions by combining medical information with your personal information.
You'll find Decision Points to help you answer questions about:
Get started learning more about your health!
Our Interactive Tools can help you make smart decisions for a healthier life. You'll find personal calculators and tools for health and fitness, lifestyle checkups, and pregnancy.
Feeling under the weather?
Use our interactive symptom checker to evaluate your symptoms and determine appropriate action or treatment.
2700 Clay Edwards Drive, Ste 240, North Kansas City, MO 64116