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Alprazolam is a high-potency
benzodiazepine that depresses the
central nervous system, causing a mood-elevating and
sedative effect and relieving feelings of anxiety. This medicine can be
Alprazolam is sometimes
prescribed for women who have
premenstrual syndrome (PMS) or
premenstrual dysphoric disorder (PMDD) when anxiety is
the main symptom and other treatments have not worked. It is only
recommended for a few days' use (no longer than the premenstrual part of the
cycle), because it loses effectiveness over time and may become addictive if
Alprazolam is considered to be
somewhat effective for PMS-related anxiety and irritability.1 But it can dull the mind and become addictive.
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
Call 911 or other emergency services right away if you have:
Call your doctor right away if you have:
Common side effects of this medicine include:
See Drug Reference for a full list of side
effects. (Drug Reference is not available in all systems.)
If you are taking alprazolam, use caution if you drive or
operate machinery. This medicine may cause drowsiness, which makes it
harder for you to concentrate.
For some women, anxiety is linked
to other PMS symptoms. Physical symptoms like weight gain or emotional symptoms
like feeling out of control may cause anxiety. Reducing these symptoms often
relieves anxiety without the need for antianxiety medicines.
used continuously, alprazolam can become addictive after a few weeks and often
must be tapered gradually to avoid symptoms of withdrawal, which can be
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Women who use this medicine during pregnancy may have a slightly higher chance of having a baby with birth defects. If you are planning to get pregnant, you and your doctor must weigh the risks of using this medicine against the risks of not treating your condition.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Kwan I, Onwude JL (2009). Premenstrual syndrome, search date July 2009. Online version of BMJ Clinical Evidence:
June 8, 2012
Sarah Marshall, MD - Family Medicine & Kirtly Jones, MD - Obstetrics and Gynecology
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